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Intermittent Fasting & Time Restricted Eating: Potential to Influence Insulin & Thus Obesity & Disease

Intermittent Fasting and Time Restricted Eating: Potential to Influence Insulin & Thus Obesity & Disease

A Biohacker’s Christmas

In keeping with the generous theme of the now upon us, “most wonderful time of the year,” we’re going to keep it a little lighter this article and bestow upon you some easily implementable biohacking tips that can enhance your quality and quantity of life, training included.

The term biohacking is a relatively new term with a wide range of interpretations and definitions depending on who you talk to.  For the purpose of this article, we will refer to biohacking as anything you can do to naturally hack into or alter the way your body works.  You can literally apply knowledge and attempt to hack into your biology, leading to beneficial internal cellular and chemical consequences.  This is no doubt a loaded topic with a variety of approaches, but for the sake of this article, we will touch on four of the main pillars of health; diet, exercise & training, sleep & stress.

 GET YOUR ZZZs

We all know how important adequate sleep can be, and how detrimental it can be to get a lack of it, especially for the recovery process, but also implicated in a host of chronic issues from mental fatigue, obesity and diabetes to immune dysfunction and cancer.  In addition to triggering your circadian rhythm by getting natural light exposure during the day, (which leads to the formation of the feel good hormone serotonin, the precursor of the sleep hormone, melatonin) it turns out exposure to artificial blue light, especially in the evening, has a major effect on how you sleep.

 According to Authority Nutrition:

“It turns out that perhaps the single biggest contributor to our collective sleep problems is the use of artificial lighting and electronics at night. These devices emit light of a blue wavelength, which tricks our brains into thinking that it is daytime.”

This wave length of light emitted by our phones, tablets, computer monitors and TVs actually inhibits the body’s ability to manufacture melatonin and thus can disrupt restorative sleep. This blue light can also induce photoreceptor damage to your eyes which is one of the main reasons we are seeing a market demand for and built in phone settings that block this type of light.

If decreasing or eliminating all unnecessary usage of blue light emitting devices in the evening isn’t possible, there are apps such as iflux or the nightshift setting on the iphone that actually block the blue lights. You can also take it a step further and purchase a pair of blue light blocking glasses to fashionably don around your domain in the evening.  This $12 pair pictured below are the ones I’ve been utilizing to optimize potential for deeper regenerative & restorative sleep; much to the comical delight of my family.

blue-light-glasses

 DON’T UNDERCUT YOUR TRAINING

We all have our reasons we get after it the way we do.  Some are motivated by performance, some to keep the weight off and stay fit.  No matter what your motivation, we never want to be put in a situation where we undercut our own efforts and performance.

We often find ourselves at a crossroads between choosing the path that favors optimal athletic performance or life longevity.  One is commonly sacrificed for the other and most are constantly striving to find that perfect balance between the two.

This is never more so true than when it comes to the fuel we chose to power our bodies.  The Gu & Gatorade roller coaster ride may do the momentary energizing trick, but it is in no way, shape or form the best way to fuel the body.  These are high carb, high sugar substances that lead to a spike in blood sugar and subsequent insulin, that peaks and dips, leading you to repeat the cycle continuously.  

It is now well known and acknowledged that spikes in blood glucose and insulin can be detrimental to your health.  What can be even more frustrating about this carb spiking habit is that the release of insulin inhibits the body’s ability to burn fat as fuel; rather it encourages the opposite, in the form of fat storage.  So you are admirably doing all you can to get after it out there, with hopes of knocking or keeping the pounds off, but are actually continuously utilizing high carb fuel sources that block your body’s ability to do so.  

Without getting into suggesting ketogeneic diets and intermittent fasting, there do exist better options to provide a steady supply of slow burning energy, without the insulin spike and subsequent blockage of fat burning.  There are more and more athletes (present company, and a number of our patients included) successfully utilizing products like UCAN, which provide this type of fuel source, divorcing you from the energy spikes and drops and enabling you to encourage your body to burn that unwanted fat for fuel.  

ucannIt should be stated, that other than making it available to our patients, we have no stake in UCAN.  However, we were so impressed with its fascinating conception out of necessity, along with the physiologically sound science and research behind it, that we were excited to add it to our own regimen and offer it to those who might also find benefit in its utilization. 

(BIOHACK BONUS: 

Let’s face it, for many people a major factor or added benefit from working out and intelligently fueling with items that enhance the body’s ability to burn fat, is the weight loss and a better body.  You can also ramp up the body’s fat burning ability by taking a 5 minute cold shower post training session.  

Many wellness enthusiasts and top thinkers implement this form of therapy first thing in the morning in order to bombard the nervous system with sensory stimuli and heighten alertness and focus.  However, it is the metabolic benefits we are focusing on here.

If you are willing to withstand the initially uncomfortable temperature, you can reap the benefits of the body generating and activating brown fat cells as a way to create heat to counteract the cold waters.  You have two main types of fat or adipose tissue, that being white and brown.  White adipose tissue is less metabolically active and plays more of an energy storage role in the form of body fat.  The more metabolically active brown fat not only generates body heat by burning calories, but has been correlated with better blood glucose control and insulin sensitivity, as well as increased metabolism.  

Top this off with having limited carbohydrates derived from a slow burning source like UCAN or even having done your pre-frozen shower workout first thing in the morning before eating and thus in a mini fasted state courtesy of the previous night’s slumber, and those calories being burned to generate the heat can be derived from the catabolic breakdown of body fat; a state of metabolic nirvana if you will.  But let’s climb out of this rabbit hole and get back on track.)

 STOP MOUTH BREATHING!

Tweaking the oft overlooked action of proper breathing is another quick easy biohack.  We touched on the benefits of proper, diaphragmatic, abdominal breathing in October’s SCR issue, and here we will take it one step further and make the case for breathing through your nose, especially when training.

When performing any physical activity we would all be well served to possess the ability to utilize the oxygen we breathe in the most efficient manner.  Subsequently, we would also greatly benefit from that oxygen being delivered to our muscles with speed and volume.   

When we breathe through our nose it triggers the release of Nitric Oxide (NO) in our bodies.  This NO cause bronchodilation, meaning it opens or expands the passage ways in your lungs, allowing more oxygen to reach the blood.  Bronchodilation is such a useful biohack that many competitive athletes utilize an inhaler normally reserved for asthmatics in order to exogenously prompt and increase this phenomenon.  Conversely, many asthmatics have found benefit and attenuation of symptoms by training themselves to nose breathe, despite the fact that on the surface it appears to be counterintuitive if you are having trouble breathing.

NO production prompted by nasal respiration also triggers vasodilation.  This is an expansion of the blood vessels to your tissues, especially those muscles being utilized during physical activity.  This is good news as it provides more oxygen rich blood that the muscles can use as fuel for energy via aerobic respiration.

Nasal breathing throughout the day will also lessen the likelihood of over breathing, which can disrupt the intricate balance of oxygen and carbon dioxide in your body.  It also increases tolerance to CO2, which can lead to more stamina and decreased occurrences of fatigue during those all-out efforts.

SLOOOW DOWN

To truly embrace a comprehensive approach to optimizing performance, the full body must be addressed.  Never is this so true than with runners, as the need to strength and stabilize outside of the repetitive uniplanar movement pattern, can prove advantageous for better form, stability, strength, and thus better function.

One of the most common excuses for not incorporating cross training is lack of time.  Being a father of two, and owner/operator of a small business, I get it.  However, if you recognize the benefits to be gained and choose to make a cross training session a priority, you can make it happen, especially if you implement the time saving strategy described below.

An S3 (Super Slow Strength) session is a time efficient and convenient way to increase strength and stability in as little as 1 to 2, 20 minute sessions per week.  You can also utilize body weight, bands, kettle balls or free weights so the inability to get to the gym can be eliminated from the list of potential excuses.

An S3 session consists of performing an exercise at you guessed it, a relatively super slow speed.  This equates to a 10 second concentric contraction, followed by a 10 second eccentric contraction.  That ends up being a 20 second repetition, and depending on the exercise and weight used, a 3 minute set if 9 reps are performed.  You can play with the configuration to your liking or goals, but if you perform just 1 set for 5 different body parts at the intervals laid out above, with a minute in between each set, you have yourself a 20 minute session.

Performing at this super slow speed enhances the cross bridging between individual muscle fibers, increasing strength and stability while limiting some of the needless wear and tear put on joints as speed increases.  Eliminating momentum and continuously having to generate power activates full body muscle recruitment and regardless of the body part worked, all muscles play a role and thus also reap the benefits. 

Still not convinced? Check out the book in the references by Dr. Doug McGuff which touches on the cardiovascular benefits obtained through this type of strength training, mcguff-s3which are noted as being comparable to those gained during a long run.  Other worthwhile benefits include increased mitochondrial density (another topic for another time, but just rest assured this is a very good thing) and improved lactic acid buffering.

If it sounds too easy, give it a shot.  As with anything I suggest, I have implemented this approach as well, and can attest to not only feeling that “good hurt” the following day, but always appreciate breaking up the sometimes mindless “picking things up to put things down” that can eventually serve as an impediment to continuing a much needed strength training session.

LAST BUT NOT LEAST…

We’ve covered biohacks aimed at sleep, exercise and diet, but we would be remiss if we didn’t touch on another major player in the whole body approach; stress.  The internal chemical consequences of stress is not restricted to the emotional or mental disruptions that we commonly refer to as stress.  Environmental toxins, food allergies and sensitivities, as well as physical stress from overtraining can all have the same consequences.  And while these are all different ways to generate stress, our biohack here will be aimed at the traditional sense of the word.

Study after study shows one of the best ways to combat the emotional and mental stressors is through some sort of meditation.  The word can intimidate or outright turn off a lot of people, but it’s best thought of as a general term for finding a way to reset or quiet and calm down mentally.  This method is highly individualized and can be thought of as anything from the aforementioned meditation to reflection, prayer, zoning out, calming the mind pond, becoming a silent observer of one’s thoughts, or simply being still and in the moment.

If you are having trouble finding your way with this, simply being outside is a good place to start.  Nature therapy where children spend more time outdoors has been shown to quiet the mind and attenuate symptoms of ADD and ADHD.  The simple act of removing your shoes and “grounding” or “earthing” also provides an anti-inflammatory and calming effect through the exchange of electrons that occurs between your body and the grass or sand.  

nature-destressThe trick is to find a method that works for you.  Do not be turned off by traditional definitions or get hung up on adhering to one method or another.  These should simply serve as ideas to apply towards your own practice.  This should be all about you and provide a moment of quiet clarity in an otherwise noisy chaotic world.  As stated, those who report meditating in some way, shape or form report benefits across the board.  And in a constantly changing world filled with inevitable stressors and the subsequent internal consequences including inflammation and disease, adding some sort of routine game plan to approach general stress is a must for any truly holistic approach.

If you still experience symptoms of stress, or other issues with your endocrine system (thyroid, sex hormones, blood sugar handling, circadian rhythm disruption, etc.) and can’t seen to get over the hump, addressing the adrenal glands may also provide some help.  We have witnessed many patients respond well to various herbs known as adaptogens and the guidance of diagnostic tests like the adrenal salivary index (ASI), enabling us to tap into and positively alter the physiology of the internal stress work horses, the adrenal glands.

So there you have it.  From one biohacker to another, I wish you happy holidays and success in implementing any of the strategies we touched on.  Obviously books could be written on each topic and you should always consult with your trusted healthcare provider before making any major changes, but hopefully these will fuel your curiosity to master one’s biology even further.  If you ever have any questions about any of these topics or more, feel free to reach out (321-848-0987Dr.RClarke@gmail.com) as these are only the tip of the iceberg as far as empowering yourself towards true holistic health.

In the meantime, perhaps I will run into you nose breathing, with blue light blocking glasses on while running barefoot on the beach.

 Enjoy the holidays and have a safe and healthy new year.

 Good luck in 2017.

 

REFERENCES:

Buteyko technique use to control asthma symptoms. Austin G(1). Nurs Times. 2013 Apr 24-30;109(16):16-7.

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. J Clin Invest. 2013;123(8):3395–3403. doi:10.1172/JCI68993.

Body By Science: a research-based program for strength training, body building and competitive fitness in 12 minutes a week / Doug McGuff /John Little; Northern River Productions. 2009

A potential natural treatment for attention-deficit/hyperactivity disorder: evidence from a national study. Kuo FE(1), Taylor AF. Am J Public Health. 2004 Sep;94(9):1580-6.

The effects of grounding (earthing) on inflammation, the immune response, wound healing, and prevention and treatment of chronic inflammatory and autoimmune diseases. J Inflamm Res. 2015 Mar 24;8:83-96. doi: 10.2147/JIR.S69656. eCollection 2015.

 

Ketogenesis: Weight Loss, Diabetes Reversal & So Much More

If you suffer with any type of ailment, one of the best things you can do is look into the science behind ketogenesis, or a fat adapted diet.  This intentional approach to altering your metabolism can prove beneficial in a multitude of ways.
For most of us, our bodies utilize the carbohydrate as the primary source of fuel.  For the most part, no matter how it’s consumed (candy bar, bread, pasta, etc.), carbs are essentially broken down into glucose molecules which trigger insulin release and subsequent glucose delivery to individual cells, to be utilized as fuel for the metabolic processes that keep us going.
The problems arise when the carbohydrates are delivered in abundance; any time, any where.  This leads to our bodies being full as far as immediate fuel needs go, and thus the excess carbohydrates broken down in the form of glucose, is stored as fat.  This flooding of glucose also leads to the already full cells reluctance or outright refusal to accept the glucose from the insulin delivering it, and thus we have the development of type II diabetes and the cascade of detrimental health effects.
Investigating and potentially implementing the ketogenic or fat adapted diet can prove advantageous to reverse the above trends.  Despite the metabolic majority, our bodies are actually able to, and some would say prefer to burn fat as fuel instead of carbohydrates.  (When fat is broken down into energy a ketone body is the molecule created, and thus explains the “ketogenic” label.)
Once the flooding of carbohydrates is mostly replaced with high quality, healthy fats (avocados, coconut oil, raw nuts and seeds, olives, etc.) the body will start to shift towards burning fat as fuel.  Another key piece to this puzzle is implementing some form of fasting.
WAIT! WAIT! WAIT! Please hear me out and don’t run for the doors due to the mention of fasting.  Fasting comes in many ways, shapes and forms and the key is to find the one that works for you.
(Always consult with your healthcare provider before potentially implementing any strategy on this site, especially the diet and lifestyle alterations included in this article).
Different combinations can be done for varying duration and frequency.  The key is to get to a point when the glucose abundance is no longer present, and your body naturally begins to switch over to burning fat for fuel, in the form of those healthy fats we mentioned, but also any excess body fat you would like to send packing.
Naturally at this point, body fat begins to be shed and blood sugar/insulin levels begin to normalize due to the break in reliance and abuse of the glucose-insulin process.  The potential benefits extend way beyond this, and can even be utilized as a way to prevent and combat cancer as it has been long documented that cancer cells thrive on glucose.  When you eliminate it’s fuel source (the carb, sugar, etc.) you essentially starve the cancer cell.
A ketogenic diet by way of intermittent fasting and macronutrient modification can also have neuro-protective effects as it encourages the proliferation of something called Brain Derived Neurotropic Factor or BDNF.  This chemical has been found to strengthen existing neuronal pathways as well as grow no ones.  Did you hear that?  The potential to grow new brain cells by intelligently modifying the diet and lifestyle.  Think of the treatment and prevention possibilities for Alzheimer’s and other neurodegenerative diseases (Parkinson’s, MS, etc.).
How about naturally enhancing HGH and testosterone for quicker muscle recovery and better performance?  Well, this is yet another way in which the ketogenic diet, when properly implemented, has been shown to be beneficial.
The list can go on as far as the benefits of switching your body’s capacity over to the optimal, preferred fuel source.  The research and results are pouring in and it is time to put to rest so many of the antiquated theories having to do with nutrition and diet.
If any of this appeals to your malleable appetite, please feel free to reach out.  We would love to discuss if this could be an advantageous idea for your unique situation and how we can successfully implement an approach based on a better understanding of the latest science when it comes to nutrition and beyond.
Be well my friends and keep your eyes and ears open.   The information and opportunity is there.  It is time to seize it.

New Insight into Weight Loss

The weight loss industry is now and forever will be alive and strong as individuals struggle to keep the pounds off.  The majority of motivation may be aesthetics, but the need to shed the excess body weight goes well beyond simply feeling good about your counterpart staring back at you in the mirror.
I become discouraged with loud and large celebrities who look to spearhead the movement of embracing obesity as being comfortable in their own skin.  Being comfortable and happy with yourself is no doubt a justifiable desire, but pushing personal acceptance of obesity is reckless to say the least.
This is not about looks or appearance either, although the message of “accepting you for you” will incorrectly cite this.  This is about an outright unhealthy state for the body to be in, and the cascade of consequences that follow.  Body fat is not a static or silent tissue; rather quite the contrary.  Adipose tissue or body fat is actually a highly active metabolic tissue that when in excess disrupts hormonal signaling (including those responsible for appetite, blood sugar and sleep regulation).
It is also a pro-inflammatory tissue, meaning the more you have the more inflamed you will be throughout the body.  This lends it’s hand not only to elevated pain levels, but it increases the common denominator behind virtually every condition known (from plantar fasciitis to neurodegenerative diseases like Alzheimer’s and Parkinson’s); inflammation.
The bottom-line here is that it’s not about the looks from a quantity and quality of life standpoint.  We are talking about a truly taxing state to ask a body to operate in, especially over time, with a list of concomitant issues that far exceeds the few listed above.
This brings us to today’s topic, which is not meant as a standalone solution to the issue, but rather another piece of the intelligently assembled, holistic puzzle.
If you’ve read any articles on this site before, you know we rightfully place an abundance of emphasis on intestinal health or “the gut.”  The major player in this system and thus our overall health is our intestinal flora, or the “probiotic” good bacteria that populate our digestive tract.
Researchers have discovered that there is a certain type of bacterial organism (firmicutes) that is more prevalent in obese individuals as opposed to the majority of bacteroidetes found in their lean counterparts.  This makes sense as firmicutes are notorious as “fat loving” bacteria with a higher propensity to digest complex carbs, extracting the energy from food and ultimately storing it as fat.
These bacteria communicate directly and indirectly with our brains, and if we are dominated with a strain of flora that thrives off of carbohydrates, the message is sent to our brains to crave and potentially overconsume these fat generating foods.  What’s more, we’ve just learned that higher levels of these firmicutes actually turn on genes (epigenetics) that not only increase the risk for obesity, but diabetes, dementia, and cardiovascular disease.
In an individual’s personal war on obesity this serves as a powerful foundational weapon.  As previously stated, obviously a variety of lifestyle strategies must be implemented to successfully attain and maintain a healthy weight.  However, this piece of information should be universally utilized in order to better control cravings from within, optimize metabolism for the goal at hand, and further substantiate a quality probiotic (and a healthy intestinal tract for it to flourish within) as one of the cornerstones to optimal health and longevity.

Don’t Detox Without Performing This Essential Step

Everyone wants to find the most efficient path to health, wellness, and longevity.  This overwhelming demand creates an abundance of products and protocols claiming to be the best.  One of the hottest buzzwords amongst these products is the detox.  And while a true detox/cleanse can not be overlooked as an intricate tool to utilize during the construction or renovation of our health, there exists a separate targeted approach that is just as, if not more important when it comes to creating an internal environment that facilitates the ability to thrive.

What we are talking about is fortifying the site where the bulk of our immune system resides.

We are talking about ensuring that maximum potential is achieved when it comes to reaping the benefits of the foods we consume via absorption of nutrients, vitamins, and minerals; and conversely minimizing the risk for nutritional deficiencies and infection.

We are talking about rebuilding the major barrier systems of our body that protect us from exposure and subsequent damage to our respiratory system, digestive tract, skin, and brain.

We are talking about optimizing and balancing the immune response and not ending up as a statistic representing the alarming growing number of seemingly idiopathic auto-immune conditions sweeping the country.

We are talking about setting the stage to grab control of glucose and insulin levels, weight and minimizing the stress response from within.

The foundation for health that we’re talking about is an optimally functioning GI (gastrointestinal) or digestive tract.  Healing and sealing any intestinal permeability or a leaky gut is absolutely essential when looking to address a countless number of issues.  Improving function on this level often times leads to an attenuation or outright termination of seemingly disconnected signs or symptoms.  When we recognize, respect and comprehend the complex interwoven matrix that is our bodies, this holistic approach becomes not only understandable but mandatory for attaining true health from the inside out.

For a number or reasons (diet [food sensitivities or high sugar/carb], antibiotics, chlorinated water, excessive use of NSAIDs, etc.) our intestinal wall can begin to falter.  This is problematic due to the fact that the majority of our immune system resides there and because it serves as a major barrier system in our bodies.

It’s relation to the three other major barrier systems (blood brain barrier, lungs, and skin) becomes blatantly obvious when gut dysfunction leads to mental fog, fatigue and forgetfulness, respiratory infections and asthma, or psoriasis and eczema, respectfully.  Further strengthening of the relationship is seen when correction of the gut dysfunction leads to a change in many of the aforementioned conditions.

This is where full acknowledgement and respect must be paid to the holistic nature of our bodies.  When one of these barrier systems is effected, damaged or dysfunctional, the effects can be seen amongst the others.  Never is this so obvious as when healing and sealing the intestines, coupled with an elimination diet leads to massive improvements or outright resolution of what appears to be unrelated issues.

If a leaky gut is left unaddressed, undigested food particles and other organisms that would otherwise be refused access, freely enter into our bloodstream.  This causes the immune system to do it’s job and launch an attack on the unwanted visitors.

The problem occurs as the immune system is called upon to perform this search and seizure so frequently that it becomes hypersensitive and begins to attack our own tissues, some of which have a similar molecular structure to the unwanted invaders.  This can manifest as allergies, asthma, rheumatoid or psoriatic arthritis, eczema, irritable bowel syndrome (Crohn’s and ulcerative colitis), hypothyroidism; even MS depending on the tissue attacked.

The longer the door is open and an attack persists, the more tissues that can suffer as condition after condition can begin to mount.  It is for these handful reasons, and countless more that fortifying the gut by way of clearing, replacing and rebuilding is at the core; the foundation of attaining optimal health.

More than 2,000 years ago, Hippocrates appeared to be onto something when he stated, “all disease begins in the gut.”  In a relatively short time, the changes I’ve witnessed personally and clinically have been nothing short of game changing for all involved.

The knowledge and path to practical implementation exists and is waiting.

As always, we’re ready when you are.